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A Trim5-cyclophilin A fusion protein found in owl monkey kidney cells can restrict HIV-1
Lv1 restriction of HIV-1 in the cells of Old World monkeys is associated with the expression of the Trim5 gene. Uniquely, in owl monkey kidney cells, HIV-1 restriction is dependent on the ability of incoming viral capsid protein to bind cyclophilin A (CypA). Cloning of the owl monkey Trim5 gene now...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC516566/ https://ncbi.nlm.nih.gov/pubmed/15326303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404640101 |
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