The leukemic fusion gene AML1-MDS1-EVI1 suppresses CEBPA in acute myeloid leukemia by activation of Calreticulin

The leukemic fusion gene AML1-MDS1-EVI1 (AME) encodes a chimeric transcription factor that results from the t(3,21)(q26;q22) translocation seen in patients with acute myeloid leukemia, with therapy-related myelodysplastic syndrome, or with chronic myeloid leukemia in blast crisis. The myeloid transc...

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Bibliographic Details
Main Authors: Helbling, Daniel, Mueller, Beatrice U., Timchenko, Nikolai A., Hagemeijer, Anne, Jotterand, Martine, Meyer-Monard, Sandrine, Lister, Andrew, Rowley, Janet D., Huegli, Barbara, Fey, Martin F., Pabst, Thomas
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC516564/
https://ncbi.nlm.nih.gov/pubmed/15326310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404731101
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