The leukemic fusion gene AML1-MDS1-EVI1 suppresses CEBPA in acute myeloid leukemia by activation of Calreticulin

The leukemic fusion gene AML1-MDS1-EVI1 (AME) encodes a chimeric transcription factor that results from the t(3,21)(q26;q22) translocation seen in patients with acute myeloid leukemia, with therapy-related myelodysplastic syndrome, or with chronic myeloid leukemia in blast crisis. The myeloid transc...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Helbling, Daniel, Mueller, Beatrice U., Timchenko, Nikolai A., Hagemeijer, Anne, Jotterand, Martine, Meyer-Monard, Sandrine, Lister, Andrew, Rowley, Janet D., Huegli, Barbara, Fey, Martin F., Pabst, Thomas
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2004
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC516564/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15326310/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0404731101
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