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A hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition
T cells generally recognize peptide antigens bound to MHC proteins through contacts with residues found within or immediately flanking the seven- to nine-residue sequence accommodated in the MHC peptide-binding groove. However, some T cells require peptide residues outside this region for activation...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC516560/ https://ncbi.nlm.nih.gov/pubmed/15331779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403371101 |
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