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Atomic structure of the entire mammalian mitochondrial complex I

Mitochondrial complex I plays a key role in cellular energy production by transferring electrons from NADH to ubiquinone coupled to proton translocation across the membrane1,2. It is the largest protein assembly of the respiratory chain with total mass of 970 kDa3. Here we present a nearly complete...

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Detalles Bibliográficos
Publicado en:Nature
Main Authors: Fiedorczuk, Karol, Letts, James A., Degliesposti, Gianluca, Kaszuba, Karol, Skehel, Mark, Sazanov, Leonid A.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5164932/
https://ncbi.nlm.nih.gov/pubmed/27595392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature19794
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