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Deletion of the Ca(2)+-activated potassium (BK) α-subunit but not the BKβ1-subunit leads to progressive hearing loss

The large conductance voltage- and Ca(2+)-activated potassium (BK) channel has been suggested to play an important role in the signal transduction process of cochlear inner hair cells. BK channels have been shown to be composed of the pore-forming α-subunit coexpressed with the auxiliary β1-subunit....

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Detalhes bibliográficos
Main Authors: Rüttiger, Lukas, Sausbier, Matthias, Zimmermann, Ulrike, Winter, Harald, Braig, Claudia, Engel, Jutta, Knirsch, Martina, Arntz, Claudia, Langer, Patricia, Hirt, Bernhard, Müller, Marcus, Köpschall, Iris, Pfister, Markus, Münkner, Stefan, Rohbock, Karin, Pfaff, Imke, Rüsch, Alfons, Ruth, Peter, Knipper, Marlies
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC516466/
https://ncbi.nlm.nih.gov/pubmed/15328414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402660101
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