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Deafness in TRβ Mutants Is Caused by Malformation of the Tectorial Membrane
Thyroid hormone receptor β (TRβ) dysfunction leads to deafness in humans and mice. Deafness in TRβ(−/−) mutant mice has been attributed to TRβ-mediated control of voltage- and Ca(2+)-activated K(+) (BK) channel expression in inner hair cells (IHCs). However, normal hearing in young constitutive BKα(...
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Asıl Yazarlar: | , , , , , , , , , , , , , , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
Society for Neuroscience
2009
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2748340/ https://ncbi.nlm.nih.gov/pubmed/19244534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3557-08.2009 |
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