Deletion of the Ca(2)+-activated potassium (BK) α-subunit but not the BKβ1-subunit leads to progressive hearing loss

The large conductance voltage- and Ca(2+)-activated potassium (BK) channel has been suggested to play an important role in the signal transduction process of cochlear inner hair cells. BK channels have been shown to be composed of the pore-forming α-subunit coexpressed with the auxiliary β1-subunit....

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Hlavní autoři: Rüttiger, Lukas, Sausbier, Matthias, Zimmermann, Ulrike, Winter, Harald, Braig, Claudia, Engel, Jutta, Knirsch, Martina, Arntz, Claudia, Langer, Patricia, Hirt, Bernhard, Müller, Marcus, Köpschall, Iris, Pfister, Markus, Münkner, Stefan, Rohbock, Karin, Pfaff, Imke, Rüsch, Alfons, Ruth, Peter, Knipper, Marlies
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC516466/
https://ncbi.nlm.nih.gov/pubmed/15328414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402660101
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