Signaling through the Prostaglandin I(2) Receptor IP Protects against Respiratory Syncytial Virus-Induced Illness

The role of prostanoids in modulating respiratory syncytial virus (RSV) infection is unknown. We found that RSV infection in mice increases production of prostaglandin I(2) (PGI(2)). Mice that overexpress PGI(2) synthase selectively in bronchial epithelium are protected against RSV-induced weight lo...

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Detalhes bibliográficos
Main Authors: Hashimoto, Koichi, Graham, Barney S., Geraci, Mark W., FitzGerald, Garret A., Egan, Karine, Zhou, Weisong, Goleniewska, Kasia, O'Neal, Jamye F., Morrow, Jason D., Durbin, Russell K., Wright, Peter F., Collins, Robert D., Suzutani, Tatsuo, Peebles, R. Stokes
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC516432/
https://ncbi.nlm.nih.gov/pubmed/15367596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.19.10303-10309.2004
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