Signaling through the Prostaglandin I(2) Receptor IP Protects against Respiratory Syncytial Virus-Induced Illness

The role of prostanoids in modulating respiratory syncytial virus (RSV) infection is unknown. We found that RSV infection in mice increases production of prostaglandin I(2) (PGI(2)). Mice that overexpress PGI(2) synthase selectively in bronchial epithelium are protected against RSV-induced weight lo...

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Autori principali: Hashimoto, Koichi, Graham, Barney S., Geraci, Mark W., FitzGerald, Garret A., Egan, Karine, Zhou, Weisong, Goleniewska, Kasia, O'Neal, Jamye F., Morrow, Jason D., Durbin, Russell K., Wright, Peter F., Collins, Robert D., Suzutani, Tatsuo, Peebles, R. Stokes
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC516432/
https://ncbi.nlm.nih.gov/pubmed/15367596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.19.10303-10309.2004
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