Synthesis and Characterization of a Native, Oligomeric Form of Recombinant Severe Acute Respiratory Syndrome Coronavirus Spike Glycoprotein

We have expressed and characterized the severe acute respiratory syndrome coronavirus (SARS-CoV) spike protein in cDNA-transfected mammalian cells. The full-length spike protein (S) was newly synthesized as an endoglycosidase H (endo H)-sensitive glycoprotein (gp170) that is further modified into an...

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Bibliografiske detaljer
Main Authors: Song, Hyun Chul, Seo, Mi-Young, Stadler, Konrad, Yoo, Byoung J., Choo, Qui-Lim, Coates, Stephen R., Uematsu, Yasushi, Harada, Takashi, Greer, Catherine E., Polo, John M., Pileri, Piero, Eickmann, Markus, Rappuoli, Rino, Abrignani, Sergio, Houghton, Michael, Han, Jang H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Structure and Assembly
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC516425/
https://ncbi.nlm.nih.gov/pubmed/15367599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.19.10328-10335.2004
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