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Forced Selection of a Human Immunodeficiency Virus Type 1 Variant That Uses a Non-Self tRNA Primer for Reverse Transcription: Involvement of Viral RNA Sequences and the Reverse Transcriptase Enzyme

Human immunodeficiency virus type 1 uses the tRNA(3)(Lys) molecule as a selective primer for reverse transcription. This primer specificity is imposed by sequence complementarity between the tRNA primer and two motifs in the viral RNA genome: the primer-binding site (PBS) and the primer activation s...

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Detalhes bibliográficos
Main Authors: Abbink, Truus E. M., Beerens, Nancy, Berkhout, Ben
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC516392/
https://ncbi.nlm.nih.gov/pubmed/15367637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.19.10706-10714.2004
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