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A Structured RNA Motif Is Involved in Correct Placement of the tRNA(3)(Lys) Primer onto the Human Immunodeficiency Virus Genome

Human immunodeficiency virus type 1 (HIV-1) reverse transcription is primed by the cellular tRNA(3)(Lys) molecule that binds with its 3′-terminal 18 nucleotides to the fully complementary primer-binding site (PBS) on the viral RNA genome. Besides this complementarity, annealing of the primer may be...

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Detalhes bibliográficos
Main Authors: Beerens, Nancy, Klaver, Bep, Berkhout, Ben
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC111704/
https://ncbi.nlm.nih.gov/pubmed/10666253
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