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Polynucleotide Kinase-Phosphatase (PNKP) Mutations and Neurologic Disease

A variety of human neurologic diseases are caused by inherited defects in DNA repair. In many cases, these syndromes almost exclusively impact the nervous system, underscoring the critical requirement for genome stability in this tissue. A striking example of this is defective enzymatic activity of...

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Detalhes bibliográficos
Publicado no:Mech Ageing Dev
Main Authors: Dumitrache, Lavinia C., McKinnon, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161711/
https://ncbi.nlm.nih.gov/pubmed/27125728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2016.04.009
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