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Polynucleotide Kinase-Phosphatase (PNKP) Mutations and Neurologic Disease

A variety of human neurologic diseases are caused by inherited defects in DNA repair. In many cases, these syndromes almost exclusively impact the nervous system, underscoring the critical requirement for genome stability in this tissue. A striking example of this is defective enzymatic activity of...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Mech Ageing Dev
Päätekijät: Dumitrache, Lavinia C., McKinnon, Peter J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161711/
https://ncbi.nlm.nih.gov/pubmed/27125728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2016.04.009
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