Targeting DNA Flap Endonuclease 1 to Impede Breast Cancer Progression

DNA flap endonuclease 1 (FEN1) plays critical roles in maintaining genome stability and integrity by participating in both DNA replication and repair. Suppression of FEN1 in cells leads to the retardation of DNA replication and accumulation of unrepaired DNA intermediates, resulting in DNA double st...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:EBioMedicine
Hlavní autoři: He, Lingfeng, Zhang, Yilan, Sun, Hongfang, Jiang, Feng, Yang, Huan, Wu, Huan, Zhou, Ting, Hu, Sencai, Kathera, Chandra Sekhar, Wang, Xiaojun, Chen, Haoyan, Li, Hongzhi, Shen, Binghui, Zhu, Yongqiang, Guo, Zhigang
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161424/
https://ncbi.nlm.nih.gov/pubmed/27852524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.11.012
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky