Targeting DNA Flap Endonuclease 1 to Impede Breast Cancer Progression

DNA flap endonuclease 1 (FEN1) plays critical roles in maintaining genome stability and integrity by participating in both DNA replication and repair. Suppression of FEN1 in cells leads to the retardation of DNA replication and accumulation of unrepaired DNA intermediates, resulting in DNA double st...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: He, Lingfeng, Zhang, Yilan, Sun, Hongfang, Jiang, Feng, Yang, Huan, Wu, Huan, Zhou, Ting, Hu, Sencai, Kathera, Chandra Sekhar, Wang, Xiaojun, Chen, Haoyan, Li, Hongzhi, Shen, Binghui, Zhu, Yongqiang, Guo, Zhigang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161424/
https://ncbi.nlm.nih.gov/pubmed/27852524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.11.012
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados