Targeting DNA Flap Endonuclease 1 to Impede Breast Cancer Progression

DNA flap endonuclease 1 (FEN1) plays critical roles in maintaining genome stability and integrity by participating in both DNA replication and repair. Suppression of FEN1 in cells leads to the retardation of DNA replication and accumulation of unrepaired DNA intermediates, resulting in DNA double st...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:EBioMedicine
Päätekijät: He, Lingfeng, Zhang, Yilan, Sun, Hongfang, Jiang, Feng, Yang, Huan, Wu, Huan, Zhou, Ting, Hu, Sencai, Kathera, Chandra Sekhar, Wang, Xiaojun, Chen, Haoyan, Li, Hongzhi, Shen, Binghui, Zhu, Yongqiang, Guo, Zhigang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2016
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161424/
https://ncbi.nlm.nih.gov/pubmed/27852524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.11.012
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