Targeting DNA Flap Endonuclease 1 to Impede Breast Cancer Progression

DNA flap endonuclease 1 (FEN1) plays critical roles in maintaining genome stability and integrity by participating in both DNA replication and repair. Suppression of FEN1 in cells leads to the retardation of DNA replication and accumulation of unrepaired DNA intermediates, resulting in DNA double st...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EBioMedicine
Egile Nagusiak: He, Lingfeng, Zhang, Yilan, Sun, Hongfang, Jiang, Feng, Yang, Huan, Wu, Huan, Zhou, Ting, Hu, Sencai, Kathera, Chandra Sekhar, Wang, Xiaojun, Chen, Haoyan, Li, Hongzhi, Shen, Binghui, Zhu, Yongqiang, Guo, Zhigang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2016
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161424/
https://ncbi.nlm.nih.gov/pubmed/27852524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.11.012
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