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Nuclear DNA damage signalling to mitochondria in ageing
Mitochondrial dysfunction is a hallmark of ageing, and mitochondrial maintenance may lead to increased healthspan. Emerging evidence suggests a crucial role for signalling from the nucleus to mitochondria (NM signalling) in regulating mitochondrial function and ageing. An important initiator of NM s...
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| Veröffentlicht in: | Nat Rev Mol Cell Biol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5161407/ https://ncbi.nlm.nih.gov/pubmed/26956196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm.2016.14 |
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