Efficient and Accurate Multiple-Phenotype Regression Method for High Dimensional Data Considering Population Structure

A typical genome-wide association study tests correlation between a single phenotype and each genotype one at a time. However, single-phenotype analysis might miss unmeasured aspects of complex biological networks. Analyzing many phenotypes simultaneously may increase the power to capture these unme...

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Bibliographic Details
Published in:Genetics
Main Authors: Joo, Jong Wha J., Kang, Eun Yong, Org, Elin, Furlotte, Nick, Parks, Brian, Hormozdiari, Farhad, Lusis, Aldons J., Eskin, Eleazar
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2016
Subjects:
Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161272/
https://ncbi.nlm.nih.gov/pubmed/27770036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.189712
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