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Synthetic tRNA(Lys,3) as the replication primer for the HIV-1(HXB2) and HIV-1(Mal) genomes

In order to determine the contribution of modified bases on the efficiency with which tRNA(Lys,3) is used in vitro as the HIV-1 replication primer, the properties of synthetic derivatives prepared by three independent methods were compared to the natural, i.e. fully modified, tRNA. When prepared dir...

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Autori principali: Miller, Jennifer T., Khvorova, Anastasia, Scaringe, Stephen A., Le Grice, Stuart F. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC516074/
https://ncbi.nlm.nih.gov/pubmed/15342789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh813
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