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The effect of eukaryotic release factor depletion on translation termination in human cell lines

Two competing events, termination and readthrough (or nonsense suppression), can occur when a stop codon reaches the A-site of a translating ribosome. Translation termination results in hydrolysis of the final peptidyl-tRNA bond and release of the completed nascent polypeptide. Alternatively, readth...

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Detalhes bibliográficos
Main Authors: Janzen, Deanna M., Geballe, Adam P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC516063/
https://ncbi.nlm.nih.gov/pubmed/15326224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh791
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