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Inhibition of Translation Termination Mediated by an Interaction of Eukaryotic Release Factor 1 with a Nascent Peptidyl-tRNA

Expression of the human cytomegalovirus UL4 gene is inhibited by translation of a 22-codon-upstream open reading frame (uORF2). The peptide product of uORF2 acts in a sequence-dependent manner to inhibit its own translation termination, resulting in persistence of the uORF2 peptidyl-tRNA linkage. Co...

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Hlavní autoři: Janzen, Deanna M., Frolova, Lyudmila, Geballe, Adam P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC139875/
https://ncbi.nlm.nih.gov/pubmed/12446775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.24.8562-8570.2002
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