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The effect of eukaryotic release factor depletion on translation termination in human cell lines
Two competing events, termination and readthrough (or nonsense suppression), can occur when a stop codon reaches the A-site of a translating ribosome. Translation termination results in hydrolysis of the final peptidyl-tRNA bond and release of the completed nascent polypeptide. Alternatively, readth...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC516063/ https://ncbi.nlm.nih.gov/pubmed/15326224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh791 |
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