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DNA ligases ensure fidelity by interrogating minor groove contacts
DNA ligases, found in both prokaryotes and eukaryotes, covalently link the 3′-hydroxyl and 5′-phosphate ends of duplex DNA segments. This reaction represents a completion step for DNA replication, repair and recombination. It is well established that ligases are sensitive to mispairs present on the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC516055/ https://ncbi.nlm.nih.gov/pubmed/15328364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh781 |
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