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Probing minor groove recognition contacts by DNA polymerases and reverse transcriptases using 3-deaza-2′-deoxyadenosine
Standard nucleobases all present electron density as an unshared pair of electrons to the minor groove of the double helix. Many heterocycles supporting artificial genetic systems lack this electron pair. To determine how different DNA polymerases use the pair as a substrate specificity determinant,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC407825/ https://ncbi.nlm.nih.gov/pubmed/15107492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh542 |
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