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Probing minor groove recognition contacts by DNA polymerases and reverse transcriptases using 3-deaza-2′-deoxyadenosine

Standard nucleobases all present electron density as an unshared pair of electrons to the minor groove of the double helix. Many heterocycles supporting artificial genetic systems lack this electron pair. To determine how different DNA polymerases use the pair as a substrate specificity determinant,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hendrickson, Cynthia L., Devine, Kevin G., Benner, Steven A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC407825/
https://ncbi.nlm.nih.gov/pubmed/15107492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh542
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