Analysis of HIV-1 Vpr determinants responsible for cell growth arrest in Saccharomyces cerevisiae

BACKGROUND: The HIV-1 genome encodes a well-conserved accessory gene product, Vpr, that serves multiple functions in the retroviral life cycle, including the enhancement of viral replication in nondividing macrophages, the induction of G2 cell-cycle arrest, and the modulation of HIV-1-induced apopto...

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Bibliographic Details
Main Authors: Yao, Xiao-Jian, Rougeau, Nicole, Duisit, Ghislaine, Lemay, Julie, Cohen, Éric A
Format: Artigo
Language:Inglês
Published: BioMed Central 2004
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC516023/
https://ncbi.nlm.nih.gov/pubmed/15312229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-1-21
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