Nrf2 inhibits epithelial-mesenchymal transition by suppressing snail expression during pulmonary fibrosis

Epithelial-mesenchymal transition (EMT) is a phenotype conversion that plays a critical role in the development of pulmonary fibrosis (PF). It is known that snail could regulate the progression of EMT. Nuclear factor erythroid 2 related factor 2 (Nrf2), a key regulator of antioxidant defense system,...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Zhou, Wencheng, Mo, Xiaoting, Cui, Wenhui, Zhang, Zhihui, Li, Delin, Li, Liucheng, Xu, Liang, Yao, Hongwei, Gao, Jian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159829/
https://ncbi.nlm.nih.gov/pubmed/27982105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38646
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