Restoration of FBP1 suppressed Snail-induced epithelial to mesenchymal transition in hepatocellular carcinoma

Fructose-1,6-bisphosphatase (FBP1), one of the rate-limiting gluconeogenic enzymes, plays critical roles in several cancers and is treated as a tumour suppressor. However, its role in hepatocellular carcinoma (HCC) is unclear. Here, we demonstrated that FBP1 was significantly inhibited during Snail-...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Liu, Gao-Min, Li, Qiao, Zhang, Peng-Fei, Shen, Shun-Li, Xie, Wen-Xuan, Chen, Bin, Wu, Jian, Hu, Wen-Jie, Huang, Xiao-Yong, Peng, Bao-Gang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235921/
https://ncbi.nlm.nih.gov/pubmed/30429463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1165-x
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