Chargement en cours...
The role of the unusual threonine string in the conversion of prion protein
The conversion of normal prion protein (PrP) into pathogenic PrP conformers is central to prion disease, but the mechanism remains unclear. The α-helix 2 of PrP contains a string of four threonines, which is unusual due to the high propensity of threonine to form β-sheets. This structural feature wa...
Enregistré dans:
| Publié dans: | Sci Rep |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2016
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5159806/ https://ncbi.nlm.nih.gov/pubmed/27982059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38877 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|