A link between double-strand break-related repair and V(D)J recombination: the scid mutation.

We show here that mammalian site-specific recombination and DNA-repair pathways share a common factor. The effects of DNA-damaging agents on cell lines derived from mice homozygous for the scid (severe combined immune deficiency) mutation were studied. Surprisingly, all scid cell lines exhibited a p...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Hendrickson, E A, Qin, X Q, Bump, E A, Schatz, D G, Oettinger, M, Weaver, D T
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1991
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51597/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1709732/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.10.4061
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