A link between double-strand break-related repair and V(D)J recombination: the scid mutation.

We show here that mammalian site-specific recombination and DNA-repair pathways share a common factor. The effects of DNA-damaging agents on cell lines derived from mice homozygous for the scid (severe combined immune deficiency) mutation were studied. Surprisingly, all scid cell lines exhibited a p...

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Hlavní autoři: Hendrickson, E A, Qin, X Q, Bump, E A, Schatz, D G, Oettinger, M, Weaver, D T
Médium: Artigo
Jazyk:Inglês
Vydáno: 1991
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC51597/
https://ncbi.nlm.nih.gov/pubmed/1709732
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