Base excision repair and double strand break repair cooperate to modulate the formation of unrepaired double strand breaks in mouse brain

Abstract We lack the fundamental information needed to understand how DNA damage in the brain is generated and how it is controlled over a lifetime in the absence of replication check points. To address these questions, here, we integrate cell-type and region-specific features of DNA repair activity...

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Hlavní autoři:	Aris A. Polyzos, Ana Cheong, Jung Hyun Yoo, Lana Blagec, Sneh M. Toprani, Zachary D. Nagel, Cynthia T. McMurray
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2024-09-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-024-51906-5
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