A link between double-strand break-related repair and V(D)J recombination: the scid mutation.

We show here that mammalian site-specific recombination and DNA-repair pathways share a common factor. The effects of DNA-damaging agents on cell lines derived from mice homozygous for the scid (severe combined immune deficiency) mutation were studied. Surprisingly, all scid cell lines exhibited a p...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Hendrickson, E A, Qin, X Q, Bump, E A, Schatz, D G, Oettinger, M, Weaver, D T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51597/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1709732/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.10.4061
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!