Rad51 and Rad54 promote noncrossover recombination between centromere repeats on the same chromatid to prevent isochromosome formation

Centromeres consist of DNA repeats in many eukaryotes. Non-allelic homologous recombination (HR) between them can result in gross chromosomal rearrangements (GCRs). In fission yeast, Rad51 suppresses isochromosome formation that occurs between inverted repeats in the centromere. However, how the HR...

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Udgivet i:Nucleic Acids Res
Main Authors: Onaka, Atsushi T., Toyofuku, Naoko, Inoue, Takahiro, Okita, Akiko K., Sagawa, Minami, Su, Jie, Shitanda, Takeshi, Matsuyama, Rei, Zafar, Faria, Takahashi, Tatsuro S., Masukata, Hisao, Nakagawa, Takuro
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Genome Integrity, Repair and Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159554/
https://ncbi.nlm.nih.gov/pubmed/27697832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw874
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