Rad51 and Rad54 promote noncrossover recombination between centromere repeats on the same chromatid to prevent isochromosome formation

Centromeres consist of DNA repeats in many eukaryotes. Non-allelic homologous recombination (HR) between them can result in gross chromosomal rearrangements (GCRs). In fission yeast, Rad51 suppresses isochromosome formation that occurs between inverted repeats in the centromere. However, how the HR...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Onaka, Atsushi T., Toyofuku, Naoko, Inoue, Takahiro, Okita, Akiko K., Sagawa, Minami, Su, Jie, Shitanda, Takeshi, Matsuyama, Rei, Zafar, Faria, Takahashi, Tatsuro S., Masukata, Hisao, Nakagawa, Takuro
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2016
Предметы:
Genome Integrity, Repair and Replication
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159554/
https://ncbi.nlm.nih.gov/pubmed/27697832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw874
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