Coordinated Activities of Multiple Myc-dependent and Myc-independent Biosynthetic Pathways in Hepatoblastoma

Hepatoblastoma (HB) is associated with aberrant activation of the β-catenin and Hippo/YAP signaling pathways. Overexpression of mutant β-catenin and YAP in mice induces HBs that express high levels of c-Myc (Myc). In light of recent observations that Myc is unnecessary for long-term hepatocyte proli...

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Publicat a:J Biol Chem
Autors principals: Wang, Huabo, Lu, Jie, Edmunds, Lia R., Kulkarni, Sucheta, Dolezal, James, Tao, Junyan, Ranganathan, Sarangarajan, Jackson, Laura, Fromherz, Marc, Beer-Stolz, Donna, Uppala, Radha, Bharathi, Sivakama, Monga, Satdarshan P., Goetzman, Eric S., Prochownik, Edward V.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
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Papers of the Week
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159488/
https://ncbi.nlm.nih.gov/pubmed/27738108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.754218
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