Neutrophils are Essential in Short Hairpin RNA of Indoleamine 2,3- Dioxygenase Mediated-antitumor Efficiency

Indoleamine 2,3-dioxygenase (IDO) is a rate limiting enzyme in tryptophan-degrading pathways and IDO activity results in immune suppression. Targeting IDO is a strategy of cancer immunotherapies. Our previous studies demonstrate that delivery of short hairpin against IDO (IDO shRNA) suppresses tumor...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Liu, Kuan-Ting, Liu, Yao-Hua, Liu, Hsin-Liang, Chong, Inn-Wen, Yen, Meng-Chi, Kuo, Po-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159481/
https://ncbi.nlm.nih.gov/pubmed/27922590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.105
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