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Substrate specificity characterization for eight putative nudix hydrolases. Evaluation of criteria for substrate identification within the Nudix family

The nearly 50,000 known Nudix proteins have a diverse array of functions, of which the most extensively studied is the catalyzed hydrolysis of aberrant nucleotide triphosphates. The functions of 171 Nudix proteins have been characterized to some degree, although physiological relevance of the assaye...

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Foilsithe in:Proteins
Main Authors: Nguyen, Vi N., Park, Annsea, Xu, Anting, Srouji, John R., Brenner, Steven E., Kirsch, Jack F.
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5158307/
https://ncbi.nlm.nih.gov/pubmed/27618147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25163
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