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High glucose facilitated endothelial heparanase transfer to the cardiomyocyte modifies its cell death signature
AIMS: The secretion of enzymatically active heparanase (Hep(A)) has been implicated as an essential metabolic adaptation in the heart following diabetes. However, the regulation and function of the enzymatically inactive heparanase (Hep(L)) remain poorly understood. We hypothesized that in response...
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| Publicado no: | Cardiovasc Res |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5157136/ https://ncbi.nlm.nih.gov/pubmed/27979811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvw211 |
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