Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age‐related anabolic resistance to exercise in humans

KEY POINTS: Resistance exercise training (RET) is one of the most effective strategies for preventing declines in skeletal muscle mass and strength with age. Hypertrophic responses to RET with age are diminished compared to younger individuals. In response to 6 weeks RET, we found blunted hypertroph...

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Vydáno v:J Physiol
Hlavní autoři: Brook, Matthew S., Wilkinson, Daniel J., Mitchell, William K., Lund, Jonathan N., Phillips, Bethan E., Szewczyk, Nathaniel J., Greenhaff, Paul L., Smith, Kenneth, Atherton, Philip J.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Muscle
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157077/
https://ncbi.nlm.nih.gov/pubmed/27654940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272857
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