Human skeletal muscle is refractory to the anabolic effects of leucine during the postprandial muscle-full period in older men

Leucine modulates muscle protein synthesis (MPS), with potential to facilitate accrual/maintenance of muscle mass. Animal models suggest that leucine boluses shortly after meals may prolong MPS and delay onset of a “muscle-full” state. However, the effects of nutrient “top-ups” in humans, and partic...

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Bibliografiske detaljer
Udgivet i:Clin Sci (Lond)
Main Authors: Mitchell, W. Kyle, Phillips, Bethan E., Hill, Ian, Greenhaff, Paul, Lund, Jonathan N., Williams, John P., Rankin, Debbie, Wilkinson, Daniel J., Smith, Kenneth, Atherton, Philip J.
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869244/
https://ncbi.nlm.nih.gov/pubmed/28982725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20171230
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