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The double-domain cytidine deaminase APOBEC3G is a cellular site-specific RNA editing enzyme
APOBEC3G is a cytidine deaminase with two homologous domains and restricts retroelements and HIV-1. APOBEC3G deaminates single-stranded DNAs via its C-terminal domain, whereas the N-terminal domain is considered non-catalytic. Although APOBEC3G is known to bind RNAs, APOBEC3G-mediated RNA editing ha...
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Publicado no: | Sci Rep |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5156925/ https://ncbi.nlm.nih.gov/pubmed/27974822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39100 |
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