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Dissecting Torsin/cofactor function at the nuclear envelope: a genetic study
The human genome encodes four Torsin ATPases, the functions of which are poorly understood. In this study, we use CRISPR/Cas9 engineering to delete all four Torsin ATPases individually and in combination. Using nuclear envelope (NE) blebbing as a phenotypic measure, we establish a direct correlation...
Tallennettuna:
| Julkaisussa: | Mol Biol Cell |
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| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The American Society for Cell Biology
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5156537/ https://ncbi.nlm.nih.gov/pubmed/27798237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-07-0511 |
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