Torsin ATPase deficiency leads to defects in nuclear pore biogenesis and sequestration of MLF2

Nuclear envelope herniations (blebs) containing FG-nucleoporins and ubiquitin are the phenotypic hallmark of Torsin ATPase manipulation. Both the dynamics of blebbing and the connection to nuclear pore biogenesis remain poorly understood. We employ a proteomics-based approach to identify myeloid leu...

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Vydáno v:J Cell Biol
Hlavní autoři: Rampello, Anthony J., Laudermilch, Ethan, Vishnoi, Nidhi, Prophet, Sarah M., Shao, Lin, Zhao, Chenguang, Lusk, C. Patrick, Schlieker, Christian
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265317/
https://ncbi.nlm.nih.gov/pubmed/32342107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201910185
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