Beneficial Effects of Combined AT(1) Receptor/Neprilysin Inhibition (ARNI) Versus AT(1) Receptor Blockade Alone in the Diabetic Eye

PURPOSE: Dysfunction of the renin-angiotensin system (RAS) contributes to pathogenesis of diabetic retinopathy (DR). Yet RAS blockers have only limited beneficial effects on progression of DR in clinical trials. The natriuretic peptide system offsets RAS, so that enhancing the activity of this syste...

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Bibliografski detalji
Izdano u:Invest Ophthalmol Vis Sci
Glavni autori: Prasad, Tuhina, Roksnoer, Lodi C. W., Zhu, Ping, Verma, Amrisha, Li, Yiming, Batenburg, Wendy W., de Vries, René, Danser, A. H. Jan, Li, Qiuhong
Format: Artigo
Jezik:Inglês
Izdano: The Association for Research in Vision and Ophthalmology 2016
Teme:
Physiology and Pharmacology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5156511/
https://ncbi.nlm.nih.gov/pubmed/27951594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-20289
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