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Combined Renin Inhibition/(Pro)Renin Receptor Blockade in Diabetic Retinopathy- A Study in Transgenic (mREN2)27 Rats

Dysfunction of renin-angiotensin system (RAS) contributes to the pathogenesis of diabetic retinopathy (DR). Prorenin, the precursor of renin is highly elevated in ocular fluid of diabetic patients with proliferative retinopathy. Prorenin may exert local effects in the eye by binding to the so-called...

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Sonraí Bibleagrafaíochta
Main Authors: Batenburg, Wendy W., Verma, Amrisha, Wang, Yunyang, Zhu, Ping, van den Heuvel, Mieke, van Veghel, Richard, Danser, A. H. Jan, Li, Qiuhong
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072720/
https://ncbi.nlm.nih.gov/pubmed/24968134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100954
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