Beneficial Effects of Combined AT(1) Receptor/Neprilysin Inhibition (ARNI) Versus AT(1) Receptor Blockade Alone in the Diabetic Eye

PURPOSE: Dysfunction of the renin-angiotensin system (RAS) contributes to pathogenesis of diabetic retinopathy (DR). Yet RAS blockers have only limited beneficial effects on progression of DR in clinical trials. The natriuretic peptide system offsets RAS, so that enhancing the activity of this syste...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Prasad, Tuhina, Roksnoer, Lodi C. W., Zhu, Ping, Verma, Amrisha, Li, Yiming, Batenburg, Wendy W., de Vries, René, Danser, A. H. Jan, Li, Qiuhong
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2016
Assuntos:
Physiology and Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5156511/
https://ncbi.nlm.nih.gov/pubmed/27951594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-20289
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