Φορτώνει......
Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair
Base excision repair (BER) is the most prominent DNA repair pathway in human mitochondria. BER also results in a temporary generation of AP-sites, single-strand breaks and nucleotide gaps. Thus, incomplete BER can result in the generation of DNA repair intermediates that can disrupt mitochondrial DN...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | DNA Repair (Amst) |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5156482/ https://ncbi.nlm.nih.gov/pubmed/24674627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2014.01.015 |
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