The contribution of pUL74 to growth of human cytomegalovirus is masked in the presence of RL13 and UL128 expression

The glycoproteins gH and gL of human cytomegalovirus (HCMV) form a complex either with pUL74 (trimeric complex) or with proteins of the UL128 locus (pentameric complex). While the pentameric complex is dispensable for viral growth in fibroblasts, deletion of pUL74 causes a small plaque phenotype in...

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Udgivet i:J Gen Virol
Main Authors: Laib Sampaio, Kerstin, Stegmann, Cora, Brizic, Ilija, Adler, Barbara, Stanton, Richard J., Sinzger, Christian
Format: Artigo
Sprog:Inglês
Udgivet: Microbiology Society 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5156331/
https://ncbi.nlm.nih.gov/pubmed/27050420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000475
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