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Mutational Mapping of pUL131A of Human Cytomegalovirus Emphasizes Its Central Role for Endothelial Cell Tropism

The UL131A protein is part of a pentameric variant of the gcIII complex in the virion envelope of human cytomegalovirus (HCMV), which has been found essential for efficient entry into endothelial cells (ECs). Using a systematic mutational scanning approach, we aimed to define peptide motifs within t...

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Détails bibliographiques
Auteurs principaux: Schuessler, Andrea, Sampaio, Kerstin Laib, Straschewski, Sarah, Sinzger, Christian
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255870/
https://ncbi.nlm.nih.gov/pubmed/22031943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05354-11
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