Src kinase as a mediator of convergent molecular abnormalities leading to NMDAR hypoactivity in schizophrenia

Numerous investigations support decreased glutamatergic signaling as a pathogenic mechanism of schizophrenia: yet molecular underpinnings for such dysregulation are largely unknown. In the postmortem dorsolateral prefrontal cortex, we found striking decreases in tyrosine phosphorylation of N-methyl-...

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Bibliografske podrobnosti
izdano v:Mol Psychiatry
Main Authors: Banerjee, Anamika, Wang, Hoau-Yan, Borgmann-Winter, Karin E., MacDonald, Mathew L., Kaprielian, Hagop, Stucky, Andres, Kvasic, Jessica, Egbujo, Chijioke, Ray, Rabindranath, Talbot, Konrad, Hemby, Scott E, Siegel, Steven J., Arnold, Steven E., Sleiman, Patrick, Chang, Xiao, Hakonarson, Hakon, Gur, Raquel E., Hahn, Chang-Gyu
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5156326/
https://ncbi.nlm.nih.gov/pubmed/25330739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2014.115
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